Did Robert Mallon invent the technology used in messenger RNA vaccines? This is what it is
asserts itself In a widely circulated text about the vaccination of children against Covid-19. In this document, published on December 11, the American scientist in particular asserts that spike proteins are “toxic”, an assertion denied by scientific research.
However, the text was widely shared on social networks, with Robert Mallon being introduced as the “inventor of RNA” or “the inventor of mRNA technology”. Here is an example of an authority argument.
If Robert Mallon played a role in knowing the messenger RNA, his work is part of a scientific dynasty, as journalist Fabrice Delay described in his book The Messenger RNA revolution, new vaccines and treatments *. As such, it is difficult to describe him as the “inventor of RNA vaccines”.
He asserts that “dozens and dozens of researchers contributed” to the development of techniques for using messenger RNA 20 minutes Science journalist. Prior to Robert Malone and his work in the late 1980s, scientists had been looking at this RNA messenger for nearly three decades. In 1961, researchers from the Pasteur Institute
emit The hypothesis of messenger RNA, a year later, is confirmed by experiments. If this discovery is significant, it is because “then we carry the molecule that makes the link between DNA and proteins,” as Fabrice Delay notes in his book.
Bring messenger RNA to cells
When Robert Malone started his work, researchers at the time were trying to figure out how to get messenger RNA into cells to produce proteins. A few years ago, in 1978 in Great Britain, he was a researcher Uses Liposomes, a vesicle with lipids in them, for insertion of messenger RNA into these mice cells.
Robert Malone, a young researcher at the Salk Institute, will do it first in the laboratory. He chose to take synthetic messenger RNA, a technology that makes it possible to more easily reproduce messenger RNA, as well as positively charged lipids. The cultured cell will then produce the proteins. Between 1987 and 1990, Robert Mallon was involved in research and even started a bit on transfection, explains Fabrice Delay. Transfection is the technology that makes it possible to synthesize RNA that encodes a specific protein. “
Publications in reputable magazines
This progress described in an article Published in 1989 in Reference Review penny I signed up with other researchers. In the same year, Robert Malone repeated the experiment this time with frog embryos. He will then conduct the experiment with the mice’s muscles, which will be the subject
from the post In prestigious income temper nature.
This successful passage of experience in the laboratory, From a farm cell, to an experiment in vivo, in the living organism, “is the contribution” of Robert Malone to the development of future technologies using mRNA, developed Fabrice Delay with 20 minutes.
Using messenger RNA as a treatment?
Then Robert Malone realized that mRNA could be used as a “cure”, remembertemper nature In an article published in September 2021. Blurred vision at that time, when research is more focused on DNA and where investors view messenger RNA as too “unstable”. In addition, large-scale synthesis of mRNA, which is essential for therapy, is still poorly controlled.
Finally, Robert Mallon would leave the Salk Institute at the end of the 1980s over patent history. Then he continues the search, as evidenced by his page The world of Google, but turns to DNA and other areas of research.
More than thirty years passed between the publication of Robert Mallon’s work and the approval of the Messenger RNA vaccines Moderna and Pfizer/BioNTech to fight Covid-19. Contracts during which the research is more advanced. If Robert Malone’s work opens the door, it is the tests developed by “dozens of researchers” that have resulted in the technology currently used in inoculation.
*Published September 29th by Odile Jacob . Editions.
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